Wednesday, March 28, 2012

Special hormone released by bone cells plays an important role in blood sugar regulation

by: Dr. David Jockers

Most people have viewed bones as inanimate structures within the body that merely play a role in providing structural integrity to the body. New research is revealing just how dynamic bone structure is to the nervous, immune and endocrine system. A bone released hormone is now considered by researchers one of the foremost players in controlling blood sugar and inflammation.

Poor blood sugar signaling leads to the formation of advanced glycolytic enzymes (AGE's). AGE's are created through non-enzymatic formation of sugar molecules and amino acids. AGE's are produced in abundance when blood sugar is chronically elevated. These AGE's induce significant free radical damage that damage bone collagen.

Fat cells release a few hormones to help regulate energy metabolism. The most well-known hormone released by fat cells is leptin. Leptin receptors reside in the hypothalamus and respond by initiating the feeling of satiety. As fat cells begin to grow (while we eat a meal) they release leptin. When enough leptin interacts with the hypothalamic receptor it stops the feelings of hunger. Additionally, leptin interaction with the hypothalamus also initiates the use of fat as an energy source. Read more...

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