(HealthDay News) -- Certain drugs used to treat rheumatoid arthritis (RA) provide a powerful, previously unknown, benefit for the immune system, say University of Rochester Medical Center researchers.
They found that drugs known as anti-TNF compounds -- including Enbrel, Humira and Remicade -- help reduce the activity of abnormal B cells that play a role in autoimmune diseases such as RA and lupus. TNF is a chemical messenger that fires up the immune system. Anti-TNF drugs inhibit TNF.
The findings, published in the Jan. 15 issue of The Journal of Immunology, suggest that these drugs improve the health of patients in a way that hadn't been recognized, the researchers said.
"The most important considerations for any drug are: Is it safe, and does it work? The answer is certainly 'yes' to both questions for these anti-TNF compounds. The drugs have revolutionized the treatment of patients with rheumatoid arthritis. But it also turns out that, even though millions of patients been treated with these medications, we really haven't understood to a significant degree how they actually work," research co-leader Dr. Ignacio Sanz, a professor of medicine, microbiology and immunology, said in a prepared statement.
Sanz and his colleagues studied 45 adults with RA and 22 healthy adults. Some of the RA patients received the anti-TNF medication etanercept (Enbrel), some received an older medication called methotrexate, and others received both drugs.
Among patients who took etanercept, there was a 40 percent drop in the percentage of B cells in lymph tissue. The RA patients who took etanercept also had about 75 percent fewer germinal centers, and the germinal centers that did exist in these patients were smaller and less organized than those in patients who didn't receive anti-TNF therapy.
Germinal centers are structures in the lymph system that appear when people have infections. These centers produce B cells, which the body uses to mark invaders for destruction. In healthy people, germinal centers fade away after recovery from an infection. But in people with RA and other chronic autoimmune diseases, germinal centers remain active.
"This is a critical piece of the immune system. Germinal centers are where crucial education of the B cell takes place -- where they learn which cells to attack and which ones not to. Dysregulation in germinal center reactions may play a role in many autoimmune diseases," study co-leader Dr. Jennifer Anolik, an assistant professor of medicine, said in a prepared statement.
Anti-TNF drugs appear to disrupt the formation of special cells (follicular dendritic cells) that link germinal centers, which decreases the number of abnormal B cells, Anolik said.
"There is a lot of excitement about the role of B cells in autoimmune disease. The connection between TNF-targeted therapy and B cells in rheumatoid arthritis really hasn't been appreciated," she said.
Anolik is about to launch a study to compare how two different anti-TNF drugs affect B cells in RA patients. The findings could help explain why some RA patients respond well to certain drugs but not others.
More information
The U.S. National Institute of Allergy and Infectious Diseases has more about autoimmune disorders.
Wednesday, January 30, 2008
Friday, January 25, 2008
Pet Turtles Linked to Rise in Salmonella Infections
(HealthDay News) -- Small pet turtles were to blame for 103 cases of Salmonella infection in the second half of last year, mostly in young children, U.S. health officials said Thursday.
But the true number of infections with the potentially fatal bacteria is undoubtedly much higher, officials added.
Even though the sale of small turtles has been banned in the United States since 1975, the number of these reptiles being purchased for children has been increasing, according to the U.S. Centers for Disease Control and Prevention.
"This is a larger number of cases than we would usually see," said Julie Harris, a CDC Epidemic Intelligence Service Officer. "We haven't documented such a large number of cases before associated with turtle exposure."
No deaths have been reported, but the infections led to the hospitalization of dozens of children, the CDC said.
The number of turtles owned by Americans has almost doubled in the last five years to more than 2 million, Harris said. This, despite the fact that "there is a ban on the sale of turtles that are under 4 inches in length," she said.
The 103 cases that Harris and colleagues reported in the Jan. 25 issue of the CDC's Morbidity and Mortality Weekly Report represent just a fraction of the total number of salmonella infections from pet turtles, she said.
According to the report, cases were reported in all but 15 states, with most cases occurring in California, Illinois, Pennsylvania and Texas.
Two of the infected children included a 13-year-old girl and a 15-year-old girl who became stricken after swimming in an unchlorinated in-ground pool owned by the family of the older girl. Two pet turtles, purchased at a South Carolina pet store and owned by the family of the older teen, were allowed to swim in the pool, the CDC reported.
Harris said many people aren't aware of the risk of Salmonella infections from pet turtles. "Only 20 percent of these cases [in the report] said they were aware there was a connection between Salmonella infection and reptile exposure," she said.
Up to 90 percent of turtles carry Salmonella, Harris said. "This is a very serious infection, especially for small children," she added.
The infection is spread from contact with the turtles, but the contact doesn't have to be direct, Harris said. "We have one case where a baby was bathed in a sink that turtle waste was disposed in," she said.
In some cases, the children put the turtle in their mouth. In other cases, children became sick from just living in the same house with a turtle or other infected family members. Salmonella can live on surfaces for weeks, Harris noted.
Adults can get sick from Salmonella, Harris said, but children get much sicker, and some can die, she said. "Small children should not be allowed to come into contact with turtles, the outcome is too dangerous and the risk is too high," she said.
According to the CDC, Salmonella infection remains a major public health problem in the United States. Each year, 1.4 million cases are reported, an estimated 15,000 people are hospitalized, and 400 Americans die.
Gastrointestinal symptoms such as vomiting and diarrhea, caused by the bacteria, typically begin 12 to 36 hours after exposure and generally last for two to seven days.
Reptiles and amphibians, including turtles, account for about 6 percent of all Salmonella cases and 11 percent of cases for those under 21.
One infectious-disease expert strongly advised parents not to buy these turtles as pets for their children.
"This is a problem that has been with us for more than 40 years," said Dr. Pascal James Imperato, the distinguished service professor and chair of the department of preventive medicine and community health and director of the master of public health program at the State University of New York Downstate Medical Center in New York City.
Children tend to handle these turtles a great deal, Imperato said. "Their fingers come into contact with all the material on the turtle and in the water. Then. there is finger-to-mouth contact, and they acquire the infection," he said.
Imperato said that to protect themselves, people who handle these turtles should wash their hands after touching the animals. But Salmonella-contaminated water can be splashed onto surfaces and cause the germ to spread.
Also, most people aren't likely to wash their hands thoroughly after they have handled a turtle or come into contact with contaminated objects or water, he said.
"The best strategy is not to purchase these turtles," Imperato said.
More information
For more on the Salmonella-turtle connection, visit the U.S. Centers for Disease Control and Prevention.
But the true number of infections with the potentially fatal bacteria is undoubtedly much higher, officials added.
Even though the sale of small turtles has been banned in the United States since 1975, the number of these reptiles being purchased for children has been increasing, according to the U.S. Centers for Disease Control and Prevention.
"This is a larger number of cases than we would usually see," said Julie Harris, a CDC Epidemic Intelligence Service Officer. "We haven't documented such a large number of cases before associated with turtle exposure."
No deaths have been reported, but the infections led to the hospitalization of dozens of children, the CDC said.
The number of turtles owned by Americans has almost doubled in the last five years to more than 2 million, Harris said. This, despite the fact that "there is a ban on the sale of turtles that are under 4 inches in length," she said.
The 103 cases that Harris and colleagues reported in the Jan. 25 issue of the CDC's Morbidity and Mortality Weekly Report represent just a fraction of the total number of salmonella infections from pet turtles, she said.
According to the report, cases were reported in all but 15 states, with most cases occurring in California, Illinois, Pennsylvania and Texas.
Two of the infected children included a 13-year-old girl and a 15-year-old girl who became stricken after swimming in an unchlorinated in-ground pool owned by the family of the older girl. Two pet turtles, purchased at a South Carolina pet store and owned by the family of the older teen, were allowed to swim in the pool, the CDC reported.
Harris said many people aren't aware of the risk of Salmonella infections from pet turtles. "Only 20 percent of these cases [in the report] said they were aware there was a connection between Salmonella infection and reptile exposure," she said.
Up to 90 percent of turtles carry Salmonella, Harris said. "This is a very serious infection, especially for small children," she added.
The infection is spread from contact with the turtles, but the contact doesn't have to be direct, Harris said. "We have one case where a baby was bathed in a sink that turtle waste was disposed in," she said.
In some cases, the children put the turtle in their mouth. In other cases, children became sick from just living in the same house with a turtle or other infected family members. Salmonella can live on surfaces for weeks, Harris noted.
Adults can get sick from Salmonella, Harris said, but children get much sicker, and some can die, she said. "Small children should not be allowed to come into contact with turtles, the outcome is too dangerous and the risk is too high," she said.
According to the CDC, Salmonella infection remains a major public health problem in the United States. Each year, 1.4 million cases are reported, an estimated 15,000 people are hospitalized, and 400 Americans die.
Gastrointestinal symptoms such as vomiting and diarrhea, caused by the bacteria, typically begin 12 to 36 hours after exposure and generally last for two to seven days.
Reptiles and amphibians, including turtles, account for about 6 percent of all Salmonella cases and 11 percent of cases for those under 21.
One infectious-disease expert strongly advised parents not to buy these turtles as pets for their children.
"This is a problem that has been with us for more than 40 years," said Dr. Pascal James Imperato, the distinguished service professor and chair of the department of preventive medicine and community health and director of the master of public health program at the State University of New York Downstate Medical Center in New York City.
Children tend to handle these turtles a great deal, Imperato said. "Their fingers come into contact with all the material on the turtle and in the water. Then. there is finger-to-mouth contact, and they acquire the infection," he said.
Imperato said that to protect themselves, people who handle these turtles should wash their hands after touching the animals. But Salmonella-contaminated water can be splashed onto surfaces and cause the germ to spread.
Also, most people aren't likely to wash their hands thoroughly after they have handled a turtle or come into contact with contaminated objects or water, he said.
"The best strategy is not to purchase these turtles," Imperato said.
More information
For more on the Salmonella-turtle connection, visit the U.S. Centers for Disease Control and Prevention.
Tuesday, January 22, 2008
Saline Nasal Wash Helps Kids Fight Colds, Flu
(HealthDay News) -- Rinsing with a special saline nasal wash made from Atlantic seawater improves symptoms in children with colds and flu, and may prevent recurrence of these infections, a new study claims.
"We brush our teeth every day, however, we do not pay attention to our noses -- a potential gate for infection," said study co-author Dr. Jana Skoupa, of Pharma Projects in Prague, Czech Republic. "Nasal wash should be used, based on our findings, immediately."
The study seems to confirm what many doctors already know.
"We have recommended this for years. This study gives some objective evidence," said Dr. Jonathan Field, emeritus director of the pediatric allergy and asthma clinic at New York University/Bellevue Medical Center in New York City.
An alternative to the many cough and cold medications that line drugstore shelves comes not a moment too soon.
Just last week, the U.S. Food and Drug Administration issued an advisory stating that over-the-counter cough and cold medicines should not be given to infants and children under the age of 2. The agency has not come to a final decision on the use of such products in children aged 2 to 11.
"This is very promising, but there need to be more studies to confirm what the authors have found," Dr. Tom DeWitt, director of general pediatrics at Cincinnati Children's Hospital Medical Center. "It is a suggestion that it may be an alternative to cold preparations that the FDA [recently issued a public health advisory about]."
The saline technique could provide a more holistic alternative to such over-the-counter medications, and has the added advantage of having little downside and not contributing to the growing problem of antibiotic resistance.
The study, published in the January issue of the Archives of Otolaryngology-Head & Neck Surgery, involved about 400 children aged 6 to 10 with colds or the flu. The children were randomly assigned to receive either standard medication plus the nasal wash, or standard medication alone.
The nasal wash formula was given six times a day for eight weeks, then three times a day for the next four weeks.
By the second visit, patients receiving the nasal wash had less stuffy and runny noses. By eight weeks, those in this group had less severe sore throats, coughs, nasal obstructions and secretions.
Also, after week eight, only 9 percent of children in the saline group were using fever-reducing drugs, compared with 33 percent in the control group; only 5 percent were using decongestants, versus 47 percent in the control group; and only 6 percent of saline recipients were using antibiotics, compared with 21 percent in the control group. Children using the nasal wash also had shorter illnesses and fewer missed school days.
Compliance, however, may become an issue outside the context of a clinical study. "They did it six times a day," DeWitt pointed out. "How many parents are going to do that six times a day?"
The trial was funded by French company Goemar Laboratoires, which makes the product, Physiomer, that used in the study.
"As far as I know, Physiomer is not available in the U.S. It is the leading brand in Europe," Skoupa said. "The manufacturing process uses electro-dialysis (not simple dilution of seawater) to achieve isotonicity. This results in preserving the majority of minerals and trace elements in similar concentrations to seawater from the Atlantic Ocean."
An isotonic solution has the same concentration of salt as the human body.
"I would not just simply expect a normal saline solution to be the same thing," DeWitt said.
More information
The Medical College of Wisconsin has more on respiratory infections in children.
"We brush our teeth every day, however, we do not pay attention to our noses -- a potential gate for infection," said study co-author Dr. Jana Skoupa, of Pharma Projects in Prague, Czech Republic. "Nasal wash should be used, based on our findings, immediately."
The study seems to confirm what many doctors already know.
"We have recommended this for years. This study gives some objective evidence," said Dr. Jonathan Field, emeritus director of the pediatric allergy and asthma clinic at New York University/Bellevue Medical Center in New York City.
An alternative to the many cough and cold medications that line drugstore shelves comes not a moment too soon.
Just last week, the U.S. Food and Drug Administration issued an advisory stating that over-the-counter cough and cold medicines should not be given to infants and children under the age of 2. The agency has not come to a final decision on the use of such products in children aged 2 to 11.
"This is very promising, but there need to be more studies to confirm what the authors have found," Dr. Tom DeWitt, director of general pediatrics at Cincinnati Children's Hospital Medical Center. "It is a suggestion that it may be an alternative to cold preparations that the FDA [recently issued a public health advisory about]."
The saline technique could provide a more holistic alternative to such over-the-counter medications, and has the added advantage of having little downside and not contributing to the growing problem of antibiotic resistance.
The study, published in the January issue of the Archives of Otolaryngology-Head & Neck Surgery, involved about 400 children aged 6 to 10 with colds or the flu. The children were randomly assigned to receive either standard medication plus the nasal wash, or standard medication alone.
The nasal wash formula was given six times a day for eight weeks, then three times a day for the next four weeks.
By the second visit, patients receiving the nasal wash had less stuffy and runny noses. By eight weeks, those in this group had less severe sore throats, coughs, nasal obstructions and secretions.
Also, after week eight, only 9 percent of children in the saline group were using fever-reducing drugs, compared with 33 percent in the control group; only 5 percent were using decongestants, versus 47 percent in the control group; and only 6 percent of saline recipients were using antibiotics, compared with 21 percent in the control group. Children using the nasal wash also had shorter illnesses and fewer missed school days.
Compliance, however, may become an issue outside the context of a clinical study. "They did it six times a day," DeWitt pointed out. "How many parents are going to do that six times a day?"
The trial was funded by French company Goemar Laboratoires, which makes the product, Physiomer, that used in the study.
"As far as I know, Physiomer is not available in the U.S. It is the leading brand in Europe," Skoupa said. "The manufacturing process uses electro-dialysis (not simple dilution of seawater) to achieve isotonicity. This results in preserving the majority of minerals and trace elements in similar concentrations to seawater from the Atlantic Ocean."
An isotonic solution has the same concentration of salt as the human body.
"I would not just simply expect a normal saline solution to be the same thing," DeWitt said.
More information
The Medical College of Wisconsin has more on respiratory infections in children.
Saturday, January 19, 2008
Bone-Strengthening Drugs May Be Overprescribed
(HealthDay News) -- Drug companies exaggerate the benefits and downplay the risks of prescribing bone-strengthening drugs for women whose bones are weakened but who do not have osteoporosis, a new report claims.
Drugs such as raloxifene, alendronate and risedronate do reduce the risk of fractures of women with osteoporosis, according to the article in the Jan. 19 issue of BMJ.
"But what they [drug makers] do is to argue that the effect of treating pre-osteoporosis [osteopenia] and osteoporosis is similar," explained study co-author Dr. Pablo Alonso-Coello, a family practitioner at Hospital Sant-Pau in Barcelona. However, many women with osteopenia have such a low risk of fractures that drug treatment would provide almost no benefit, he noted.
"This move to treat pre-osteoporosis raises serious questions about the benefit-risk relationship for low-risk individuals and about the costs of medicalizing and potentially medicating an enormous group of healthy people," the report said. Osteopenia is thought to affect almost half of older women, the study noted.
The study authors looked at four studies, all of which found benefits in giving osteoporosis drugs to women with osteopenia. But those reports exaggerated the benefits, often by reporting risk reduction in relative rather than absolute terms, Alonso-Coello said.
For example, the absolute risk of a woman with osteoporosis having a fracture in a given year might be 10 percent, he said. "The effect of an osteoporosis drug is to lower that risk by half, so the absolute benefit is a 5 percent reduction. But in women with pre-osteoporosis, the risk of fracture is very low, say 1 percent a year, so if you lower that by half, you go down to an 0.5 percent absolute reduction," he explained.
One study cited in the paper claimed a 75 percent relative reduction in the risk of fracture, Alonso-Coello said. The absolute risk reduction was 0.9 percent, meaning that up to 270 women with pre-osteoporosis would have to be treated with drugs for three years to avoid a single fracture.
The study also found that the research played down the potentially harmful side effects of these drugs; in one case, a re-analysis of data on raloxifene, a selective estrogen receptor modulator (SERM), made no mention of the increased risk for blood clots.
Just this month, the U.S. Food and Drug Administration issued an alert on bisphosphonates, the class of osteoporosis drugs that include alendronate and risedronate, warning that the medications can cause severe bone pain.
Even the study authors themselves are open to question, Alonso-Coello said. "Many of the authors are industry people, employees of the drug companies, which casts some doubt on them," he said.
Drug companies now are marketing the drugs in Europe to women with osteopenia, he said. According to the report, two companies had to modify their promotional material after complaints from Alonso-Coello and fellow researcher Ray Moynihan, a conjoint lecturer in the Faculty of Health at the University of Newcastle, Callaghan, New South Wales, Australia.
The World Health Organization is taking steps to help women with osteopenia make decisions about drug treatment. "WHO is moving to calculate absolute risk," Alonso-Coello said. "I contacted them recently and was told they might report really soon, as early as next January.
They are working with well-developed equations to calculate the risk of fracture, the same sort of risk factors as for cardiovascular disease."
More information
All aspects of osteoporosis are explored by the National Osteoporosis Foundation.
Drugs such as raloxifene, alendronate and risedronate do reduce the risk of fractures of women with osteoporosis, according to the article in the Jan. 19 issue of BMJ.
"But what they [drug makers] do is to argue that the effect of treating pre-osteoporosis [osteopenia] and osteoporosis is similar," explained study co-author Dr. Pablo Alonso-Coello, a family practitioner at Hospital Sant-Pau in Barcelona. However, many women with osteopenia have such a low risk of fractures that drug treatment would provide almost no benefit, he noted.
"This move to treat pre-osteoporosis raises serious questions about the benefit-risk relationship for low-risk individuals and about the costs of medicalizing and potentially medicating an enormous group of healthy people," the report said. Osteopenia is thought to affect almost half of older women, the study noted.
The study authors looked at four studies, all of which found benefits in giving osteoporosis drugs to women with osteopenia. But those reports exaggerated the benefits, often by reporting risk reduction in relative rather than absolute terms, Alonso-Coello said.
For example, the absolute risk of a woman with osteoporosis having a fracture in a given year might be 10 percent, he said. "The effect of an osteoporosis drug is to lower that risk by half, so the absolute benefit is a 5 percent reduction. But in women with pre-osteoporosis, the risk of fracture is very low, say 1 percent a year, so if you lower that by half, you go down to an 0.5 percent absolute reduction," he explained.
One study cited in the paper claimed a 75 percent relative reduction in the risk of fracture, Alonso-Coello said. The absolute risk reduction was 0.9 percent, meaning that up to 270 women with pre-osteoporosis would have to be treated with drugs for three years to avoid a single fracture.
The study also found that the research played down the potentially harmful side effects of these drugs; in one case, a re-analysis of data on raloxifene, a selective estrogen receptor modulator (SERM), made no mention of the increased risk for blood clots.
Just this month, the U.S. Food and Drug Administration issued an alert on bisphosphonates, the class of osteoporosis drugs that include alendronate and risedronate, warning that the medications can cause severe bone pain.
Even the study authors themselves are open to question, Alonso-Coello said. "Many of the authors are industry people, employees of the drug companies, which casts some doubt on them," he said.
Drug companies now are marketing the drugs in Europe to women with osteopenia, he said. According to the report, two companies had to modify their promotional material after complaints from Alonso-Coello and fellow researcher Ray Moynihan, a conjoint lecturer in the Faculty of Health at the University of Newcastle, Callaghan, New South Wales, Australia.
The World Health Organization is taking steps to help women with osteopenia make decisions about drug treatment. "WHO is moving to calculate absolute risk," Alonso-Coello said. "I contacted them recently and was told they might report really soon, as early as next January.
They are working with well-developed equations to calculate the risk of fracture, the same sort of risk factors as for cardiovascular disease."
More information
All aspects of osteoporosis are explored by the National Osteoporosis Foundation.
Tuesday, January 15, 2008
Additional Benefits of Curcumin
Some researchers say curcumin inhibits angiogenesis, the formation of new blood vessels, which tumors use to nourish themselves as they spread. (Mod Med 1998 Jun:4(6); 376-83).
Scientists at M.D. Anderson Hospital, in Texas, wrote in 2003: Extensive research over the last 50 years has indicated curcumin can both prevent and treat cancer.
This anti-cancer potential of curcumin stems from its ability to suppress a proliferation of a wide variety of : tumor cells. down-regulate transcription factors FF-KappaB, Ap-1 and Egr-1. down regulate the expression of COX-2, LOX, NOS< MMp-g, uPA, TNF, chemokines, cell surface adhesion molecules and cyclin D1. down-regulate growth factor receptors such as (EGFR and HER-2) and inhibit the activity of c-Jun N terminal Kinase, protein tyrosine Kinases and protein serine/threonine Kinases.
more information's: http://www.dreddy-clinic.com/
Scientists at M.D. Anderson Hospital, in Texas, wrote in 2003: Extensive research over the last 50 years has indicated curcumin can both prevent and treat cancer.
This anti-cancer potential of curcumin stems from its ability to suppress a proliferation of a wide variety of : tumor cells. down-regulate transcription factors FF-KappaB, Ap-1 and Egr-1. down regulate the expression of COX-2, LOX, NOS< MMp-g, uPA, TNF, chemokines, cell surface adhesion molecules and cyclin D1. down-regulate growth factor receptors such as (EGFR and HER-2) and inhibit the activity of c-Jun N terminal Kinase, protein tyrosine Kinases and protein serine/threonine Kinases.
more information's: http://www.dreddy-clinic.com/
Additional Benefits of Curcumin
Some researchers say curcumin inhibits angiogenesis, the formation of new blood vessels, which tumors use to nourish themselves as they spread. (Mod Med 1998 Jun:4(6); 376-83).
Scientists at M.D. Anderson Hospital, in Texas, wrote in 2003: Extensive research over the last 50 years has indicated curcumin can both prevent and treat cancer.
This anti-cancer potential of curcumin stems from its ability to suppress a proliferation of a wide variety of : tumor cells. down-regulate transcription factors FF-KappaB, Ap-1 and Egr-1. down regulate the expression of COX-2, LOX, NOS< MMp-g, uPA, TNF, chemokines, cell surface adhesion molecules and cyclin D1. down-regulate growth factor receptors such as (EGFR and HER-2) and inhibit the activity of c-Jun N terminal Kinase, protein tyrosine Kinases and protein serine/threonine Kinases.
more information's: http://www.dreddy-clinic.com/
Scientists at M.D. Anderson Hospital, in Texas, wrote in 2003: Extensive research over the last 50 years has indicated curcumin can both prevent and treat cancer.
This anti-cancer potential of curcumin stems from its ability to suppress a proliferation of a wide variety of : tumor cells. down-regulate transcription factors FF-KappaB, Ap-1 and Egr-1. down regulate the expression of COX-2, LOX, NOS< MMp-g, uPA, TNF, chemokines, cell surface adhesion molecules and cyclin D1. down-regulate growth factor receptors such as (EGFR and HER-2) and inhibit the activity of c-Jun N terminal Kinase, protein tyrosine Kinases and protein serine/threonine Kinases.
more information's: http://www.dreddy-clinic.com/
Wednesday, January 09, 2008
Kama Yogi
YOUR BODY IS YOUR TEMPLE! Maintain It Through Proven Ancient Practices for Sexual Enhancement! CHARAKA, THE AUTHOR OF ANCIENT AYURVEDIC TEXTS, WROTE . . .
"The healthy life has three main pillars - a balanced diet, mental hygiene, and a healthy not allowed life. " Kama Yogi's Powerful Techniques Give Significant, Invigorating, and Enduring Results! If you want to enjoy extraordinary not allowed and reduced chance of low not allowed drive and lack of vigor, vitality, and raw sexual energy, there is proven help available.
India's men and women have been reaping the powerful benefits of YOGA for the past 5,000 years!
The 63-page Kama Yogi eBook with 165 color photographs offers a set of ancient spiritual practices geared towards the attainment of sexual vigor, improved vitality, and increased libido. It will help you: Intensify Your Orgasms. Elevate Your not allowed Drive. Enhance Your Sexual Pleasure. Harden & Prolong Your Erections.
Acquire Flexibility for Lovemaking. Satisfy Desires & Be Fulfilled. Kama Yogi is a product of: 5000 years of Yogic wisdom. Tantra and Kundalini principles. Proven Yoga postures. Time-tested Meditation techniques.
Focus on physical & spiritual sexuality.
http://www.kamayogi.com/index.htm?aff=dreddyclinic
"The healthy life has three main pillars - a balanced diet, mental hygiene, and a healthy not allowed life. " Kama Yogi's Powerful Techniques Give Significant, Invigorating, and Enduring Results! If you want to enjoy extraordinary not allowed and reduced chance of low not allowed drive and lack of vigor, vitality, and raw sexual energy, there is proven help available.
India's men and women have been reaping the powerful benefits of YOGA for the past 5,000 years!
The 63-page Kama Yogi eBook with 165 color photographs offers a set of ancient spiritual practices geared towards the attainment of sexual vigor, improved vitality, and increased libido. It will help you: Intensify Your Orgasms. Elevate Your not allowed Drive. Enhance Your Sexual Pleasure. Harden & Prolong Your Erections.
Acquire Flexibility for Lovemaking. Satisfy Desires & Be Fulfilled. Kama Yogi is a product of: 5000 years of Yogic wisdom. Tantra and Kundalini principles. Proven Yoga postures. Time-tested Meditation techniques.
Focus on physical & spiritual sexuality.
http://www.kamayogi.com/index.htm?aff=dreddyclinic
Sunday, January 06, 2008
Sherpa Strength
Experience Greater Strength and Power - Guaranteed!
Try a Proprietary Formula for Muscular Growth and Stamina based on Ayurveda - the Oldest and Most Holistic, Comprehensive Medical System Available. If you want to attain extraordinary muscle strength, power, and endurance, there is proven help available.
India's men and women have been reaping the powerful benefits of Ayurveda Medicine for the past 5,000 years! Sherpa Strength is a natural supplement geared towards optimizing your total structural health, by strengthening your musculoskeletal and respiratory systems.
It will help you: Increase Your Energy & Fitness. Enhance Muscle Mass & Strength. Optimize Your Oxygen Uptake. Boost Your Endurance & Flexibility. Promote Cellular Regeneration.
Raise Your Confidence. Sherpa Strength is a product of: 5000 years of Ayurvedic wisdom.
Modern testing and research. Breakthrough encapsulation technique. Laboratory-controlled potency. Doctor-approved, carefully calibrated formula.
http://www.sherpa-strength.com/index.htm?aff=dreddyclinic
Try a Proprietary Formula for Muscular Growth and Stamina based on Ayurveda - the Oldest and Most Holistic, Comprehensive Medical System Available. If you want to attain extraordinary muscle strength, power, and endurance, there is proven help available.
India's men and women have been reaping the powerful benefits of Ayurveda Medicine for the past 5,000 years! Sherpa Strength is a natural supplement geared towards optimizing your total structural health, by strengthening your musculoskeletal and respiratory systems.
It will help you: Increase Your Energy & Fitness. Enhance Muscle Mass & Strength. Optimize Your Oxygen Uptake. Boost Your Endurance & Flexibility. Promote Cellular Regeneration.
Raise Your Confidence. Sherpa Strength is a product of: 5000 years of Ayurvedic wisdom.
Modern testing and research. Breakthrough encapsulation technique. Laboratory-controlled potency. Doctor-approved, carefully calibrated formula.
http://www.sherpa-strength.com/index.htm?aff=dreddyclinic
Wednesday, January 02, 2008
Health Tip: Make Reading a Daily Activity
(HealthDay News) - Developing reading and communication skills is a vital part of a child's growth.
The Nemours Foundation offers these suggestions for encouraging a daily dose of reading:
The Nemours Foundation offers these suggestions for encouraging a daily dose of reading:
- Keep a book or magazine with you, and encourage your child to read while running an errand or waiting for an appointment.
- Have your child read you recipes while you cook dinner, or read recipes aloud to other children.
- Encourage your child to read magazines, catalogs and other mail you receive.
- Encourage family members to write letters or emails to your child.
- Have your child read aloud to you while you clean the house or do other chores. Or, read to her while she does her chores.
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Kamaraja
